Therapeutic targets and new directions for antibodies developed for ovarian cancer
نویسندگان
چکیده
منابع مشابه
Therapeutic targets and new directions for antibodies developed for ovarian cancer
Antibody therapeutics against different target antigens are widely used in the treatment of different malignancies including ovarian carcinomas, but this disease still requires more effective agents. Improved understanding of the biological features, signaling pathways, and immunological escape mechanisms involved in ovarian cancer has emerged in the past few years. These advances, including an...
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1Departments of Pathology, Oncology and Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA 2Gynecologic Cancer Center, Department of Obstetrics and Gynecology, Cathay General Hospital, Jen-Ai Road, Taipei 10630, Taiwan 3Department of Obstetrics and Gynecology, Shimane University School of Medicine, Enyacho 89-1, Izumo 693-8501, Japan 4Division of Gyneco...
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Cancer stem cells (CSCs) have been identified as rare cellular populations in many cancers, including leukemia and solid tumors. This minor subpopulation of cancerous cells is immortal tumor-initiating cells which thought to be responsible for cancer initiation, progression, metastasis, recurrence and drug/radiation resistance. Low proliferative rate, high self-renewing capacity, differentiatio...
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ژورنال
عنوان ژورنال: mAbs
سال: 2016
ISSN: 1942-0862,1942-0870
DOI: 10.1080/19420862.2016.1219005